Market Access Africa, in partnership with the Aurum Institute and with funding from Unitaid, invites qualified and capable suppliers and manufacturers to submit proposals for the procurement and/or regulatory support of itraconazole for the treatment of histoplasmosis in Sub-Saharan Africa.

This Request for Proposals (RFP) is issued under the IMPAACT4HIV initiative to improve diagnosis and treatment of Advanced HIV Disease (AHD) in low- and middle-income countries (LMICs), specifically through increased access to antifungal treatment for histoplasmosis. The RFP includes two lots and applicants may apply for one or both.

• LOT I: Procurement –  Procurement of itraconazole tablets/capsules to the seven project countries in Africa.
• LOT II: Registration Support - Support manufacturers who are willing to submit their dossier for registration by a Stringent Regulatory Authority (SRA) or approval by the WHO Prequalification Program

Deadline for Submission

All proposals must be submitted electronically to impaact4hiv@auruminstitute.org  no later than 7 July 2025, 17:00 SAST, with the subject line: Request for Proposals – Itraconazole Procurement

Late submissions will not be accepted.

Queries

‍Questions regarding the RFP will be answered by email only within the 2 weeks following the posting of the RFP. It will not be possible to engage in telephone enquiries. All questions or clarifications must be submitted in writing to impaact4hiv@auruminstitute.org by 23 June 2025, 17:00 SAST

Responses will be consolidated and shared with all interested parties. Questions received after the deadline will not be addressed.

Download Documents

• Download the RFP Instructions
• ‍Aurum     ITR 2025

About IMPAACT4HIV

‍The Improved Access to AHD Care and Treatment for HIV (IMPAACT4HIV) project is a Unitaid-funded initiative led by the Aurum Institute, in partnership with Market Access Africa. The project aims to reduce mortality from Advanced HIV Disease by improving access to diagnostics and treatment including antifungal therapies through innovative, community- based, and country-owned models. IMPAACT4HIV focuses on increasing availability of essential commodities such as CD4 testing, CrAg, and itraconazole, and strengthening systems for equitable care in high-burden countries.

For more information about IMPAACT4HIV, please visit: Impaact4HIV